ImmunologyOncoImmunologyPeer-reviewed
High-grade serous ovarian cancer development and anti-PD-1 resistance is driven by IRE1α activity in neutrophils
Alexander Emmanuelli, Camilla Salvagno, Sung‐Min Hwang…·Juan R. Cubillos‐Ruiz
This study shows that IRE1α activity in neutrophils drives HGSOC development and anti-PD-1 resistance by promoting immune escape.
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