Author

Oktay Cakil

Centre National de la Recherche ScientifiqueORCID 0000-0002-5935-9048Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:human· 1

Frequent Co-Authors

Hervé MoineiD· 3 shared Boglárka ZámbóiD· 2 shared Amélie PitoniD· 1 shared Anastasiya Petrova· 1 shared Anne Robert· 1 shared Asmae Maachi· 1 shared Audrey Thevenin· 1 shared Bruno CharpentieriD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersMolecular Biology

Hervé MoineORCID

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3 papers

Recent·Most cited

The DGKK mRNA is a primary target of the Prader-Willi syndrome-associated snoRNA SNORD116

Soline Louis, Oktay Cakil, Audrey Thevenin, Hélène Marty, Asmae Maachi, Virginie Marty, Anne Robert, Marie-Eve Chagot, Bruno Charpentier, Xavier Manival, Isabelle Lebars, Hervé Moine, Stephane Labialle

The paper identifies DGKK as the primary target of SNORD116, showing increased DGKK RNA and protein levels upon SNORD116 depletion in human and mouse models.

bioRxiv · Oct 21, 2026 · PreprintMolecular Biology

m⁶A-dependent FMRP control of DGKκ translation underlies core Fragile X phenotypes

Oktay Cakil, Boglárka Zámbó, Tatiana Maroilley, Nathalie Drouot, Anastasiya Petrova, Luc Négroni, Gergő Gógl, Amélie Piton, Hervé Moine

The paper identifies DGKκ as a key target of FMRP regulation through m⁶A modification, showing its role in FXS phenotypes.

bioRxiv · Mar 10, 2026 · PreprintMolecular Biology

AAV-delivery of diacylglycerol kinase kappa achieves long-term rescue of Fmr1-KO mouse model deficits of fragile X syndrome

Karima Habbas, Oktay Cakil, Boglárka Zámbó, Ricardos Tabet, Fabrice Riet, Doulaye Dembélé, Jean‐Louis Mandel, Michaël Hocquemiller, Ralph Laufer, Françoise Piguet, Hervé Moine

AAV-delivered FMRP-independent DGKk corrects brain lipid homeostasis and behavioral deficits in Fmr1-KO mice.

bioRxiv · Apr 14, 2021 · PreprintNeuroscience