BioengineeringACS Applied Materials & InterfacesPeer-reviewed
Sequentially Self-Assembled Supramolecular Nanocomplexes Enable Systemic Cas9 RNP Delivery and In Vivo Tumor Genome Editing
Takumi Matsuo, Yuto Honda, Toshizumi Chino…·Nobuhiro Nishiyama
This paper develops a supramolecular nanocomplex for systemic CRISPR-Cas9 delivery, achieving higher gene editing efficiency in tumors compared to free RNPs.
DOI 10.1021/acsami.6c14858