The Neurofibrillary Tangle Maturity Scale: A Novel Framework for Tangle Pathology Evaluation in Alzheimer's Disease
Christina M. Moloney, Matthew H. Rutledge, Sydney A. Labuzan…·Melissa Erin Murray
The paper develops a tangle maturity scale to evaluate Alzheimer's disease pathology using tau antibodies and machine learning, showing early tau modifications precede advanced ones.