GenomicsDevelopmental CellPeer-reviewed
Epithelial cells of the intestine acquire cell-intrinsic inflammation signatures during ageing
Maja C. Funk, Jan Gleixner, Florian Heigwer…·Michael Boutros
This study shows that aged intestinal epithelial cells exhibit a persistent inflammation signature, marked by MHC class II upregulation and increased chromatin accessibility of inflammation-associated loci.
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