James C. Perry

The paper examines changes in calcium-binding protein-expressing neurons in the anteroventral thalamic nuclei of individuals with Down syndrome compared to controls.

This study investigates how damage to the mammillothalamic tract affects hippocampo-cortical oscillatory activity and microstructure, linking these changes to memory impairments.

The paper quantifies neuron and glial cell loss in anterior thalamic nuclei of older Down’s syndrome patients, finding a 70% neuron reduction and lesser glial loss, suggesting aging-related pathology in this region contributes to memory impairments.