Gene editing of the multi-copy H2A.B gene family by a single pair of TALENS
Nur Diana Anuar, Matthew A. Field, Sebastian Kurscheid, Lei Zhang, Edward J. Rebar, Philip D. Gregory, Josephine Bowles, Peter A. Koopman, David John Tremethick, Tatiana Soboleva
The paper tests TALEN specificity by knocking out three H2A.B genes with a single TALEN pair, demonstrating high specificity for this multi-copy gene family.
bioRxiv · Dec 13, 2017 · PreprintGenomics