MicrobiologybioRxivPreprint
Identifying and targeting the Mg-Fe-PmrAB regulatory circuit reverses phosphate starvation-driven polymyxin tolerance in Enterobacteriaceae
Guangming Zhang, Ziqing Deng, Jiezhang Jiang…·Aixin Yan
This study identifies a Mg-Fe-PmrAB regulatory circuit that mediates polymyxin tolerance in Enterobacteriaceae under phosphate starvation and shows that targeting this circuit can reverse tolerance.
DOI 10.1101/2025.08.18.670855