Author

Claire E. Coupland

Great Ormond Street HospitalORCID 0000-0002-6041-7532Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Research Focus:protein structure prediction· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

John L. RubinsteiniD· 3 shared Gautier M. CourboniD· 2 shared Justin M. Di TraniiD· 2 shared Ryan KarimiiD· 2 shared Stephanie A. BueleriD· 2 shared Yingke LiangiD· 2 shared Ana Paula Lobez Rodriguez· 1 shared Cassandra J. WongiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersBiochemistry

John L. RubinsteinORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cryo-EM of native membranes reveals an intimate connection between the Krebs cycle and respiration in mycobacteria

Justin M. Di Trani, Jiacheng Yu, Gautier M. Courbon, Ana Paula Lobez Rodriguez, Chen‐Yi Cheung, Yingke Liang, Claire E. Coupland, Stephanie A. Bueler, Gregory Murray Cook, Peter Brzezinski, John L. Rubinstein

The paper uses cryo-EM to show that malate-quinone oxidoreductase associates with the CIII2CIV2 supercomplex in mycobacteria, linking Krebs cycle and respiration.

Proceedings of the National Academy of Sciences · Feb 19, 2025Peer-reviewedBiochemistry

Vesicle Picker: A tool for efficient identification of membrane protein complexes in vesicles

Ryan Karimi, Claire E. Coupland, John L. Rubinstein

Vesicle Picker automatically identifies vesicles and selects particle locations in cryo-EM micrographs, improving efficiency for membrane protein complex analysis.

Journal of Structural Biology · Oct 30, 2024Peer-reviewedBiophysics

High resolution cryo-EM of V-ATPase in native synaptic vesicles

Claire E. Coupland, Ryan Karimi, Stephanie A. Bueler, Yingke Liang, Gautier M. Courbon, Justin M. Di Trani, Cassandra J. Wong, Rayan Saghian, Ji‐Young Youn, Lu‐Yang Wang, John L. Rubinstein

The paper determines the high-resolution structure of V-ATPase in native synaptic vesicles using cryo-EM, revealing interactions with cholesterol and synaptophysin.

Science · Jun 20, 2024Peer-reviewedBiochemistry