Molecular BiologyCell ReportsPeer-reviewed
Mechanism and evolutionary origins of Alanine-tail C-degron recognition by E3 ligases Pirh2 and CRL2-KLHDC10
Pratik Rajendra Patil, Alexander Maxwell Burroughs, Mohit Misra…·Claudio A.P. Joazeiro
The paper investigates how Pirh2 and CRL2-KLHDC10 E3 ligases recognize Ala-tails, showing conserved binding sites and convergent evolution of their recognition mechanisms.
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