Author

Robert F Wynn

ORCID 0000-0002-6046-8428Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Anu GoenkaiD· 1 shared Arunabha GhoshiD· 1 shared Eylan YutuciD· 1 shared Glenda M BeamaniD· 1 shared Gloria Lopez-CastejoniD· 1 shared Jonas Abdel-KhalikiD· 1 shared Mohsen Ali AsgariiD· 1 shared Simon A JonesiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Anu GoenkaORCID

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1 paper

Recent·Most cited

Deletion of CH25H and LIPA Genes in Human Abolishes Biosynthesis of 25-Hydroxycholesterol but not of 7alpha,25-Dihydroxysterols and Enhances Non-enzymatic Cholesterol Oxidation: Metabolic Changes are Partially Reversed by Hematopoietic Stem Cell Transplant

Eylan Yutuc, Arunabha Ghosh, Jonas Abdel-Khalik, Anu Goenka, Mohsen Ali Asgari, Gloria Lopez-Castejon, Glenda M Beaman, Robert F Wynn, William G Newman, Simon A Jones, William J Griffiths, Yuqin Wang

This study shows that deleting CH25H and LIPA genes in humans eliminates 25-hydroxycholesterol but not 7alpha,25-dihydroxysterols, and increases cholesterol oxidation, which is partially reversed by hematopoietic stem cell transplant.

medRxiv · Jul 29, 2025 · PreprintGenetic & Genomic Medicine