Author

Arunabha Ghosh

University of ManchesterORCID 0000-0002-8202-8693Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:dimensionality reduction· 1 Assay:metabolomics· 1

Frequent Co-Authors

Eylan YutuciD· 2 shared Jonas Abdel-KhalikiD· 2 shared Mohsen Ali AsgariiD· 2 shared Simon Allan JonesiD· 2 shared William James GriffithsiD· 2 shared Yuqin WangiD· 2 shared A. A. M. MorrisiD· 1 shared Anu GoenkaiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Eylan YutucORCID

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2 papers

Recent·Most cited

Deletion of CH25H and LIPA Genes in Human Abolishes Biosynthesis of 25-Hydroxycholesterol but not of 7alpha,25-Dihydroxysterols and Enhances Non-enzymatic Cholesterol Oxidation: Metabolic Changes are Partially Reversed by Hematopoietic Stem Cell Transplant

Eylan Yutuc, Arunabha Ghosh, Jonas Abdel-Khalik, Anu Goenka, Mohsen Ali Asgari, Gloria Lopez-Castejon, Glenda M Beaman, Robert F Wynn, William G Newman, Simon A Jones, William J Griffiths, Yuqin Wang

This study shows that deleting CH25H and LIPA genes in humans eliminates 25-hydroxycholesterol but not 7alpha,25-dihydroxysterols, and increases cholesterol oxidation, which is partially reversed by hematopoietic stem cell transplant.

medRxiv · Jul 29, 2025 · PreprintGenetic & Genomic Medicine

Rare Cholesterol Related Disorders: A Sterolomic Library for Diagnosis and Monitoring of Diseases

Mohsen Ali Asgari, Eylan Yutuc, Jonas Abdel‐Khalik, Peter J. Crick, A. A. M. Morris, Simon Allan Jones, Arunabha Ghosh, Richard Curnock, Claire Hart, Ludger J. Schöls, Silke Matysik, Ιωάννα Λαϊνά, Evan Reid, Thomas T. Warner, Belén González‐Herrero, , Yuqin Wang

The paper introduces a mass spectrometry sterolomic library to aid in diagnosing cholesterol-related inherited disorders by analyzing sterol profiles from 13 autosomal recessive disorders and predicting data for 8 more.

medRxiv · Jun 23, 2025 · PreprintGenetic & Genomic Medicine