Steve Vincent Maurice Runser

OptiCell3D infers mechanical cell properties from 3D microscopy data, showing that apical to lateral surface tension ratio predicts cell aspect ratio in epithelial tissues.

The paper introduces SimuCell3D, a 3D simulation tool for tissue mechanics that enables detailed study of cell organization and biomechanical parameters in various tissue geometries.

The paper identifies tissue-enriched ligands involved in epithelial-endothelial crosstalk during pancreas development using scRNA-seq and computational interactomics.

The paper shows fluid flow-induced shear stress drives biased epithelial tube elongation in lung and kidney development, independent of other factors.