Mohamed Boutjdir

This study uses Cav1.3-C-terminus gene therapy to restore electrophysiological and contractile functions in hiPSC-derived cardiomyocytes with ET-1-induced heart failure.

This paper develops a microphysiological system using hiPSC-derived neurons and cardiomyocytes to model sympathetic neuro-cardiac interactions and test drug effects.

This study shows that a CACNA1D variant causes electrophysiological abnormalities in hiPSC-CMs, which are reversed by AAV6-Cav1.3-C-terminus gene therapy.