Author

Michael Mobaraki

National Institutes of HealthORCID 0000-0002-6080-7258Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:eQTL / molecular QTL mapping· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Aidan O’BrieniD· 1 shared Changhui Deng· 1 shared Daina Eiser· 1 shared Erin ChariD· 1 shared Gauri PrasadiD· 1 shared H. Efsun ArdaiD· 1 shared Hao Li· 1 shared Irene J. CollinsiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenetic & Genomic Medicine

Aidan O’BrienORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Characterization of a pancreatic cancer GWAS signal suggests PDX1 buffers stress in the exocrine pancreas

Jason W. Hoskins, Trevor A. Christensen, Daina Eiser, Erin Char, Michael Mobaraki, Aidan O’Brien, Irene J. Collins, Jun Zhong, Minal B. Patel, Gauri Prasad, H. Efsun Arda, Katelyn E. Connelly, Laufey Thora Amundadottir

This study identifies rs9581943 as a causal variant in a PDAC GWAS signal, showing it reduces PDX1 expression and impairs stress buffering in exocrine pancreatic cells.

medRxiv · Apr 15, 2026 · PreprintGenetic & Genomic Medicine

Yeast aging from a dynamic systems perspective: Analysis of single cell trajectories reveals significant interplay between nuclear size scaling, proteasome dynamics, and mitochondrial morphology

Michael Mobaraki, Changhui Deng, Jiashun Zheng, Hao Li

The paper analyzes single-cell yeast aging trajectories to show proteasome dynamics and nuclear size scaling are key predictors of lifespan and influence mitochondrial morphology.

bioRxiv · Mar 11, 2025 · PreprintBioinformatics