Déborah Gérard

EpiATLAS provides a comprehensive collection of human reference epigenomes to advance epigenomic research and understanding of cellular function and disease.

This study identifies ZFHX4 as a key regulator of midbrain dopaminergic neuron differentiation by controlling cell cycle progression through the LIN28A-miR-9 axis.

The paper identifies Parkinson's disease-associated regulatory variants in human dopaminergic neurons and shows they modulate SCARB2 and BAG3 expression.

The paper reconstructs metabolic networks across 58 human tissues and cell types using RNA-seq and epigenomic data, identifying core and cell-type-specific metabolic functions and their regulatory elements.

The paper identifies AHR and GLIS1 as key regulators of mesenchymal multipotency using temporal epigenomic and transcriptomic data from mouse bone marrow stromal cells.