Wnt5a-mediated Adipo-Cardiac Interorgan Communication in HFpEF
Anam Fatima, Faris Abusharkh, Zoe Zanetta…·Vineet Agrawal
This study identifies a novel crosstalk mechanism between cardiomyocytes and adipocytes in obesity-associated HFpEF driven by natriuretic peptide-mediated inhibition of Wnt5a release from adipocytes.