Krishna Kumar Singh

Title - ATG7 vs. ATG5: Distinct Autophagy Pathways Shaping TGF-β Signaling and Endothelial Function

This study compares the roles of ATG5 and ATG7 in modulating TGF-β signaling and endothelial function, showing distinct effects on gene expression and cellular behavior.

The effect of fatty acid binding protein-3 exposure on endothelial transcriptomics

This study examines how exposure to recombinant FABP3 affects endothelial cell transcriptomics, identifying key genes and pathways involved in immune response and angiogenesis.

BRCA2-deficiency Causes Global Transcriptomic Alterations in Endothelial Cells

This study identifies 3196 differentially expressed genes in BRCA2-deficient endothelial cells and highlights altered pathways related to cell adhesion and cytokine signaling.

Chloroquine Up-regulates Expression of SARS-CoV-2 receptor Angiotensin Converting Enzyme-2 in Endothelial Cells

This study shows chloroquine increases ACE2 expression in endothelial cells, potentially worsening SARS-CoV-2 infection in patients with cardiovascular or kidney diseases.

Protocol development for discovery of angiogenesis inhibitors via automated methods using zebrafish

This paper develops an automated high-throughput screening platform using zebrafish embryos to identify angiogenesis inhibitors, validated with I3M showing dose-dependent inhibition.