Belinda Sena Akpa

Prediction variability in physiologically based pharmacokinetic modeling of tissue disposition under deep uncertainty

The paper evaluates prediction variability in PBPK models under deep uncertainty, showing significant variation in PK statistics and model disagreement for certain chemical compounds.

Guard Cell-Enriched Phosphoproteome Reveals Phosphorylation of Endomembrane Proteins in Closed Stomata

The paper identifies phosphorylation of endomembrane proteins in closed guard cells, suggesting their role in regulating stomatal closure.

Regulation of Vacuole Fusion in Stomata by Dephosphorylation of the HOPS subunit VPS39

This study identifies phosphorylation of VPS39 as critical for regulating vacuole fusion in stomata, linking it to environmental cues and stomatal opening.

Model-based inference of a plant-specific dual role for HOPS in regulating guard cell vacuole fusion

The paper develops a quantitative model of vacuole fusion dynamics in plant guard cells to predict a dual role for HOPS in regulating SNARE complex formation and activity.