Author

Vlad Elgart

Brigham and Women's HospitalORCID 0000-0002-6102-6904Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Amit Chandra· 1 shared Huamei He· 1 shared João A. PauloiD· 1 shared Joseph LoscalzoiD· 1 shared Navdeep S. ChandeliD· 1 shared Nishith Shrimali· 1 shared Niv VigderiD· 1 shared Ram Prosad ChakrabartyiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Amit Chandra

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintAug 14, 2026

2-Hydroxyglutarate Redirects Fatty Acid Partitioning to Mitigate Lipotoxic Stress and Preserve Metabolic Fuel

Niv Vigder, Amit Chandra, Nishith Shrimali…·Joseph Loscalzo

This paper shows that 2-hydroxyglutarate (2HG) alters fatty acid partitioning, reducing lipotoxic stress by shifting fatty acids toward storage and away from oxidation and membrane synthesis.

DOI 10.64898/2026.08.12.744465

humanmouse

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