Tian Tian

This study develops covalent leader peptide probes to identify RiPP enzymes outside biosynthetic gene clusters, revealing cross-cluster enzymatic interactions.

This study designs nanobodies against SARS-CoV-2 variants using a deep generative model, identifying two neutralizing candidates.

This paper develops a yeast artificial chromosome system in K. marxianus to enhance heterologous protein expression by incorporating disulfide bond formation modules, achieving record-high glucoamylase yields.