Author

Tian Tian

Capital Medical University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

Click to filter author papers

Neuroscience· 2 Bioinformatics· 1 Genetics· 1 Molecular Biology· 1 Physiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:mouse· 4 Approach:statistical model· 3 Research Focus:spatial domain detection· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:contrastive learning· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Aicui Zhang· 1 shared Alex Tsun Lok Lui· 1 shared Baogang Yu· 1 shared Bradford C. BerkiD· 1 shared Bryan Cheuk-Yu Lee· 1 shared Caroline GutjahriD· 1 shared Chunjian Li· 1 shared Danni CheniD· 1 shared

Activity by Year

2024-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenetics

Aicui Zhang

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Ileal Gpbar1 gates depressive phenotypes via gut to brain "vagal-NTS-PVN"GABAergic axis

Lin Zhong, Yuanlu Shu, Mi Yan, Long Wang, Min Wu, Jing Wu, Song Yang, Zedong Gu, Zhongliang Chen, Guoyan Xin, Shan Guan, Tian Tian

This study identifies ileal Gpbar1 as a peripheral node that regulates depressive behaviors via a gut-to-brain GABAergic axis, showing that agonism of Gpbar1 can reverse depressive-like phenotypes.

bioRxiv · Sep 14, 2026 · PreprintNeuroscience

Mapping disease traits onto spatiotemporal domain landscapes through scalable multi-sample integration of spatial transcriptomics

Songming Zhang, Shifu Luo, Yuxiao Luo, Shuquan Su, Ling Liu, Ying Shi, Wu-Jun Li, Tian Tian, Jinyan Li

STUltra integrates spatial transcriptomics data to map disease traits onto spatiotemporal tissue landscapes, outperforming existing methods in scalability and speed.

bioRxiv · Aug 10, 2026 · PreprintBioinformatics

Tirzepatide attenuates atherosclerosis through weight loss-independent anti-inflammatory mechanisms

Shuo Chen, Shulin Wei, Tian Tian, Z.H. Liu, Meiming Su, Fan-shun Zhang, Yanjun Yin, Meijie Chen, Lu Jiang, Paul Charles Evans, Bradford C. Berk, Stefan Offermanns, Yihai Cao, Zhihua Wang, Jianping Weng, Suowen Xu

This paper shows tirzepatide reduces atherosclerosis independently of weight loss by directly targeting vascular inflammation through the cAMP/PKA/eNOS pathway.

bioRxiv · Jun 29, 2026 · PreprintPhysiology

Heterogeneous and specific localization of mRNAs at dendritic spine and its dependence on microtubule entry

Xiaojie Wang, Jiaxing Song, Jiahao Lin, Tian Tian, Alex Tsun Lok Lui, Bryan Cheuk-Yu Lee, Liang Zhang, Kwok‐On Lai

The paper investigates mRNA localization at dendritic spines and finds that specific mRNAs target different subdomains and require microtubule entry and the motor KIF5A.

bioRxiv · Mar 18, 2026 · PreprintNeuroscience

Ethylene signal-driven plant-multitrophic synergy boosts crop performance

Marcel Baer, Yanting Zhong, Baogang Yu, Tian Tian, Xiaoming He, Ling Gu, Xiaofang Huang, Elena Gallina, Isabelle Elisabeth Metzen, Marcel Bucher, Rentao Song, Caroline Gutjahr, Zhen Su, Yudelsy A.T. Moya, Nicolaus von Wirén, , Peng Yu

This study identifies ERF transcription factors as key regulators of AM fungal-induced lateral root development in maize, revealing a tripartite signaling network involving ethylene, flavonoids, and microbial synergies.

bioRxiv · Nov 28, 2025 · PreprintPlant Biology

Single-cell Characterization of DNA Hydroxymethylation of the Mouse Brain During Aging

Yali Bai, Tianjiao Yuan, Liuhao Ren, Yuhang Huan, Fa Yang, Yutong Li, Aicui Zhang, Yueyang Liu, Tian Tian, Ningxia Kang, Danni Chen, Xiaoliang Sunney Xie, Qiang Wang, Wei Chen, Yinghui Zheng, Yunlong Cao

The paper introduces Joint-Cabernet, a single-cell platform for profiling 5hmC and 5mC, and applies it to mouse brain nuclei to study DNA hydroxymethylation changes with aging.

bioRxiv · May 29, 2025 · PreprintGenetics

Neuregulin-1 Attenuates Myocardial Ischemia/Reperfusion Injury by Activating the UCP2/PINK1/LC3B-mediated Mitophagy

Xin‐Tao Li, Xinyue Li, Tian Tian, Wen‐He Yang, Yi Cheng, Kai Su, Xihua Lu, Mu Jin, Fu‐Shan Xue

This study shows that NRG-1 postconditioning protects against myocardial I/R injury by activating mitophagy through the UCP2/PINK1/LC3B pathway in rats and H9C2 cells.

bioRxiv · Oct 8, 2024 · PreprintMolecular Biology