Jungang Zhou

The paper enhances glycoprotein secretion in yeast by engineering a human-like protein quality control system, resulting in up to 12-fold increased production of therapeutic glycoproteins.

This study transfers chromosomes from Saccharomyces cerevisiae to Kluyveromyces marxianus, resulting in improved phenotypes and widespread transcriptional changes.

This paper develops a yeast artificial chromosome system in K. marxianus to enhance heterologous protein expression by incorporating disulfide bond formation modules, achieving record-high glucoamylase yields.