Author

Xiaodong Zheng

Harbin Medical UniversityORCID 0000-0002-6103-9836Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:statistical model· 1

Frequent Co-Authors

Cui MaiD· 2 shared Lixin ZhangiD· 2 shared Chi ZhangiD· 1 shared Daling ZhuiD· 1 shared Daling ZhuiD· 1 shared Fei LiiD· 1 shared Hang YuiD· 1 shared Hanliang Sun· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersMolecular Biology

Cui MaORCID

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3 papers

Recent·Most cited

ca-circSCN8A promotes HPASMCs ferroptosis via LLPS initiated R-Loop

Mengnan Li, Yingying Hao, Xinyue Song, Huiyu Liu, Chi Zhang, Jiaqi Zhang, Hanliang Sun, Xiaodong Zheng, Lixin Zhang, Hang Yu, Cui Ma, Xijuan Zhao, Daling Zhu

This study identifies ca-circSCN8A as a promoter of ferroptosis in HPASMCs under hypoxia by forming R-loops via LLPS of ca-circSCN8A/FUS/EP300, disrupting redox balance and contributing to pulmonary hypertension.

bioRxiv · Jan 21, 2025 · PreprintMolecular Biology

Super Enhancer-driven LncRNA UNC5B-AS1 Inhibits Inflammatory Phenotypic Transition in Smooth Muscle Cells via Lactylation Modification

Xiangrui Zhu, Xiangming Pang, Xiaoying Wang, Xiaoyu Guan, Zhaosi Wang, Lixin Zhang, Xiaodong Zheng, Fei Li, Jian Mei, Langlin Ou, Yuxiang Liu, Zitong Meng, Yingli Chen, Cui Ma

This paper identifies UNC5B-AS1, a super enhancer-driven lncRNA, as a regulator of inflammatory phenotypic transition in PASMCs under hypoxia, showing its role in stabilizing mitochondrial complex IV interactions and modulating lactylation of inflammatory gene promoters.

bioRxiv · May 7, 2024 · PreprintMolecular Biology

Long Noncoding RNA-Maternally Expressed Gene 3 Contributes to Hypoxic Pulmonary Hypertension

Yan Xing, Xiaodong Zheng, Yao Shi Fu, Jing Qi, Minghui Li, Mingfei Ma, Shuang Wang, Shuzhen Li, Daling Zhu

This study identifies lncRNA-MEG3 as a contributor to hypoxic pulmonary hypertension by sequestering miR-328 and upregulating IGF1R in PASMCs.

Molecular Therapy · Aug 22, 2019Peer-reviewedMolecular Biology