MicrobiologybioRxivPreprint
Neutralizing Activity of Cervicovaginal Secretions against Herpes Simplex Virus is Mediated by Mucosal IgG and Viral Glycoprotein E and Adversely Impacted by Vaginal Dysbiosis
Aakash Mahant Mahant, Valerie Fong, Matthew S. Gromisch…·Betsy C. Herold
This study shows that cervicovaginal secretions neutralize HSV through mucosal IgG and gE interactions, which are reduced in bacterial vaginosis due to glycan loss.
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