Author

Betsy C. Herold

Albert Einstein College of MedicineORCID 0000-0001-9974-0786Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:metagenomics· 1

Frequent Co-Authors

Aakash Mahant MahantiD· 2 shared Anayeli Correa· 1 shared Andreas LuxenburgeriD· 1 shared Deepa G. ManwaniiD· 1 shared Heng PaniD· 1 shared Ian MichaeliD· 1 shared Jacob S Kazmi· 1 shared Janine Keenan· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

Aakash Mahant MahantORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Bacterial and viral gut microbiome alterations characterizemicrobiome-immune-pathophysiology axes in sickle cell disease

Zachary Flamholz, Jennifer De Los Santos, Karen Ireland, Janine Keenan, Jacob S Kazmi, Aakash Mahant Mahant, Anayeli Correa, Paul S. Frenette, Betsy C. Herold, Deepa G. Manwani, Libusha Kelly

This study identifies microbiome-immune-pathophysiology axes in sickle cell disease by analyzing bacterial and viral gut microbiome alterations.

bioRxiv · Jul 20, 2026 · PreprintImmunology

Glypican-1 upregulation elicited in response to a cell-impermeable kinase inhibitor and its overexpression enhance HIV-1 infection

Kelsey Vinzant, Natalia Cheshenko, Heng Pan, Ronald R. Cutler, Joshua N. Buckler, Andreas Luxenburger, Lawrence D. Harris, Jeffrey R. Johnson, Steven C. Almo, Betsy C. Herold

The paper identifies glypican-1 (GPC1) as a novel modulator of HIV-1 infection, showing its upregulation by a kinase inhibitor enhances viral infection through TGF-β signaling.

bioRxiv · Oct 28, 2025 · PreprintMicrobiology

Neutralizing Activity of Cervicovaginal Secretions against Herpes Simplex Virus is Mediated by Mucosal IgG and Viral Glycoprotein E and Adversely Impacted by Vaginal Dysbiosis

Aakash Mahant Mahant, Valerie Fong, Matthew S. Gromisch, Richard Hunte, Ian Michael, Jennifer T. Aguilan, Kerry Murphy, Marla J. Keller, Betsy C. Herold

This study shows that cervicovaginal secretions neutralize HSV through mucosal IgG and gE interactions, which are reduced in bacterial vaginosis due to glycan loss.

bioRxiv · May 15, 2025 · PreprintMicrobiology