Jennifer T. Aguilan

This study identifies ribosomal proteins as major substrates of starvation-induced endosomal microautophagy in Drosophila, revealing its role in metabolic adaptation.

The paper develops a structure prediction method using XL-MS data for disordered microsporidian proteins with no homologs, successfully modeling two spore wall proteins.

This study identifies the GNMT N-terminal tail and its phosphorylation at S9 as a regulatory mechanism linking folate feedback to SAM homeostasis.

This study maps the Toxoplasma gondii interactome using crosslinking mass spectrometry and machine learning, identifying 405 PPIs with high confidence and validating their biological relevance.

This study shows PRMT5 sustains histone transcription and protein synthesis during S phase, maintaining genome integrity by regulating histone H4 methylation.

This paper combines MALDI-MSI and LC-MS/MS to map spatial protein changes in murine thymus during chemotherapy, identifying key proteins involved in regeneration and immune recovery.

This study shows that cervicovaginal secretions neutralize HSV through mucosal IgG and gE interactions, which are reduced in bacterial vaginosis due to glycan loss.

This study shows that CARM1 loss in GSCs disrupts developmental programming, shifts lineage towards radial glia, and creates a dependency on NGFR/NTRK signaling, making them vulnerable to NTRK inhibitors.

This paper develops next-generation sEH-targeting PROTACs with improved potency and stability, showing effective degradation in mouse tissues.

This study shows that platelet PI3Kβ promotes breast cancer metastasis by enhancing tumor cell invasion and signaling pathways, suggesting it as a therapeutic target.

The paper identifies EXOSC4's interaction with a specific histone modification pair and shows its role in regulating non-coding transcription.

This study uses proteomics and phosphoproteomics to analyze iPSC-derived neurons and microglia from JdVS patients, identifying molecular changes linked to neurodevelopmental and psychiatric symptoms.

This study identifies MGAT4D as a protective factor for male germ cells against mild heat stress, showing that its absence increases sensitivity to heat.