Author

Rachana S. Vaidya

Washington University in St. LouisORCID 0000-0002-6120-5056Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Sade W. ClaytoniD· 2 shared Simon Y. TangiD· 2 shared Aimy SebastianiD· 1 shared Christian E. GonzaleziD· 1 shared Gabriela G. LootsiD· 1 shared Garrett W. D. EassoniD· 1 shared Kaitlyn S. BroziD· 1 shared Nicholas R. HumiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersPhysiology

Sade W. ClaytonORCID

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2 papers

Recent·Most cited

PhysiologyDisease Models & MechanismsPeer-reviewedOct 6, 2025

The transcriptome and secreted factors of the intervertebral discs in STZ HFD Type2 diabetic male mice reveal extensive inflammation

Christian E. Gonzalez, Rachana S. Vaidya, Sade W. Clayton, Simon Y. Tang

This study examines the transcriptome and secreted factors in intervertebral discs of STZ-HFD T2D mice, revealing increased inflammation and degeneration compared to controls.

9 citationstop 3%

mousebulk RNA-seq

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Cell BiologyExperimental Cell ResearchPeer-reviewedJul 30, 2025

Single cell RNA sequencing reveals a shift in cell function and maturation of endogenous and infiltrating cell types in response to acute intervertebral disc injury

Sade W. Clayton, Aimy Sebastian, Stephen P. Wilson…·Simon Y. Tang

This study uses single-cell RNA sequencing to analyze changes in cell function and maturation in the intervertebral disc after injury, identifying key cell populations and pathways involved in degeneration.

9 citationstop 2%

mousescRNA-seq

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