Author

Kaitlyn S. Broz

Washington University in St. LouisORCID 0000-0002-8096-7304Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 2 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Remy E. WalkiD· 4 shared Simon Y. TangiD· 4 shared Timothy Hung· 2 shared Aimy SebastianiD· 1 shared Alec T BeeveiD· 1 shared C. E. GonzaleziD· 1 shared Erica L. SchelleriD· 1 shared Gabriela G. LootsiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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4 shared papersBioengineering

Remy E. WalkORCID

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4 papers

Recent·Most cited

Genetic and pharmacologic modulation of RAGE rescues the diabetes-mediated impairments to bone at multiple length scales

Kaitlyn S. Broz, Timothy Hung, Remy E. Walk, Suzanne LoTempio, Katharine M. Flores, S. Y. Tang

This study shows that modulating RAGE through genetic or pharmacologic means can reverse diabetes-induced bone impairments across multiple scales.

bioRxiv · Apr 6, 2026 · PreprintBioengineering

The progression of neurovascular features and chemokine signatures of the intervertebral disc with degeneration

Remy E. Walk, Kaitlyn S. Broz, L. Jing, Ryan P. Potter, C. E. Gonzalez, Alec T Beeve, Erica L. Scheller, M.C. Gupta, Lori A. Setton, S. Y. Tang

This study tracks the temporal changes in chemokine production and neurovascular invasion in mouse intervertebral discs during degeneration following injury.

European Cells and Materials · Dec 31, 2025Peer-reviewedBioengineering

Single cell RNA sequencing reveals a shift in cell function and maturation of endogenous and infiltrating cell types in response to acute intervertebral disc injury

Sade W. Clayton, Aimy Sebastian, Stephen P. Wilson, Nicholas R. Hum, Remy E. Walk, Garrett W. D. Easson, Rachana Vaidya, Kaitlyn S. Broz, Gabriela G. Loots, Simon Y. Tang

This study uses single-cell RNA sequencing to analyze changes in cell function and maturation in the intervertebral disc after injury, identifying key cell populations and pathways involved in degeneration.

Experimental Cell Research · Jul 30, 2025Peer-reviewedCell Biology

The sex-specific effects of RAGE signaling and Type 2 Diabetes on mouse cortical bone mechanics, structure, and material properties

Timothy Hung, Kaitlyn S. Broz, Remy E. Walk, Simon Y. Tang

This study examines how RAGE signaling and Type 2 Diabetes affect cortical bone mechanics, structure, and material properties in mice, showing sex-specific improvements with RAGE ablation.

Mechanobiology in Medicine · May 13, 2025Peer-reviewedPathology