Yi Li

Spatial-DC improves spatial proteomics deconvolution by using deep learning to infer cell-type composition and reconstruct proteomic profiles from low-resolution data.

The paper identifies and characterizes a fourth type VI secretion system (H4-T6SS) in Pseudomonas aeruginosa, showing it is repressor-gated and contributes to inter- and intraspecific antagonism.

DeepSME enables private DNA-based communication by decrypting heavily modified DNA using nanopore sequencing and deep learning, achieving high precision and recall.

The paper introduces a nanopore-based codec system, Composite Hedges Nanopores (CHN), capable of handling high indel and substitution error rates for real-time DNA data readout.