Molecular BiologyMolecular Therapy OncologyPeer-reviewed
Targeting CD45 by gene-edited CAR-T cells for leukemia eradication and hematopoietic stem cell transplantation preconditioning
Valeria M. Stepanova, Dmitry V. Volkov, Daria S. Osipova…·Alexey V. Stepanov
This paper demonstrates the preclinical efficacy of CD45-targeting CAR T and NK cells for leukemia treatment and HSCT preconditioning, showing reduced fratricide through gene editing.
9 citations