Author

Daria S. Osipova

Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and ImmunologyORCID 0000-0002-9968-9332Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Alexander G. GabiboviD· 1 shared Alexey V. StepanoviD· 1 shared Ding ZhangiD· 1 shared Dmitry PershiniD· 1 shared Dmitry V. VolkoviD· 1 shared Ekaterina A. MalakhovaiD· 1 shared Elena A. KulakovskayaiD· 1 shared Georgij B. Telegin· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Alexander G. GabibovORCID

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1 paper

Recent·Most cited

Targeting CD45 by gene-edited CAR-T cells for leukemia eradication and hematopoietic stem cell transplantation preconditioning

Valeria M. Stepanova, Dmitry V. Volkov, Daria S. Osipova, Wenjian Wang, Yingqin Hou, Dmitry Pershin, Maria Fadeeva, Ekaterina A. Malakhova, Elena A. Kulakovskaya, LYU Cuicui, Zhao Mingfeng, Hongkai Zhang, Jia Xie, Ding Zhang, Ilgar Z. Mamedov, , Alexey V. Stepanov

This paper demonstrates the preclinical efficacy of CD45-targeting CAR T and NK cells for leukemia treatment and HSCT preconditioning, showing reduced fratricide through gene editing.

Molecular Therapy Oncology · Jun 27, 2024Peer-reviewedMolecular Biology