Author

Isao Kii

Shinshu UniversityORCID 0000-0002-6153-6250Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Daichi NakamuraiD· 1 shared Gaku Furuie· 1 shared Koji UmezawaiD· 1 shared Masaki KikuchiiD· 1 shared Masato Yamakawa· 1 shared Nanae Fukahori· 1 shared Ninako Kimura· 1 shared Sora Suzuki· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

Daichi NakamuraORCID

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1 paper

Recent·Most cited

BiophysicsEuropean Journal of Medicinal ChemistryPeer-reviewedMay 20, 2025

Temperature vaulting: A method for screening selective, slow- and tight-binding inhibitors targeting kinases in their non-native state

Sora Suzuki, Koji Umezawa, Gaku Furuie…·Isao Kii

This paper introduces a method called 'temperature vaulting' to screen inhibitors targeting kinases in their non-native state, demonstrating its effectiveness with the inhibitor FINDY (1) against DYRK1A.

1 citation

experimental assaydrug response / drug discovery

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