Tandem duplication of serpin genes yields functional variation and snake venom inhibitors.
Meilyn S Ward, Matthew L. Holding, Laura M. Haynes, Mark J. Margres, Marjorie D. Matocq, David Ginsburg
The paper studies gene duplication in SERPINA genes across vertebrates and shows that duplicated paralogs in rodents can inhibit snake venom proteases, suggesting adaptive functional variation.
Molecular Biology and Evolution · Oct 29, 2025Peer-reviewedEvolutionary Biology