Author

Lennard Dalit

The University of MelbourneORCID 0000-0002-6159-6640Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Joanna R. GroomiD· 3 shared Aidil ZainiiD· 2 shared Alana KirniD· 2 shared Bailey E. WilliamsiD· 2 shared Carolina AlvaradoiD· 2 shared Chin Wee TaniD· 2 shared Kim L. Good‐JacobsoniD· 2 shared Melissa J. DavisiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Joanna R. GroomORCID

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3 papers

Recent·Most cited

MLL1 directs gut-associated antibody responses to helminth and bacterial infections

Yan Zhang, Clarissa R. Chakma, Alana Kirn, David Chisanga, Jack Polmear, Aidil Zaini, Rohia Farighi, Lennard Dalit, Liang Xie, Diana López‐Ureña, Steven J. Mileto, Dena Lyras, Zaph Colby, Joanna R. Groom, Kim L. Good‐Jacobson

This study identifies MLL1 as a regulator of IgA responses to gut infections, showing its role in promoting IgA+ plasma cells and worm clearance in mice.

The Journal of Immunology · Feb 1, 2026Peer-reviewedImmunology

Divergent cytokine and transcriptional signatures control functional T follicular helper cell heterogeneity

Lennard Dalit, Chin Wee Tan, Amania A. Sheikh, Ryan B. Munnings, Lauren J. Howson, Carolina Alvarado, Tabinda Hussain, Aidil Zaini, Lucy Cooper, Alana Kirn, Lauren Hailes, Angela Nguyen, Bailey E. Williams, Ming Z. M. Zheng, Carolien E. van de Sandt, , Joanna R. Groom

The paper identifies transcriptional modules and cytokine signaling pathways that drive functional heterogeneity in T follicular helper cells across different infections.

Nature Immunology · Sep 9, 2025Peer-reviewedImmunology

Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection

Benjamin J. Broomfield, Chin Wee Tan, Raymond Z. Qin, Hanna Abberger, Brigette C. Duckworth, Carolina Alvarado, Lennard Dalit, Chee Leng Lee, Rekha Shandre Mugan, Zihnil Adha Islamy Mazrad, Hiromi Muramatsu, Liana Mackiewicz, Bailey E. Williams, Jinjin Chen, Asuka Takanashi, , Joanna R. Groom

This paper shows that temporarily blocking type I interferon during viral infection boosts CD8+ T cell memory and vaccine effectiveness by promoting TSCM cell formation.

The Journal of Experimental Medicine · Feb 5, 2025Peer-reviewedImmunology