Author

Brigette C. Duckworth

The University of MelbourneORCID 0000-0002-2134-3542Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Bailey E. WilliamsiD· 3 shared Benjamin J. BroomfieldiD· 3 shared Joanna R. GroomiD· 3 shared Carolina AlvaradoiD· 2 shared Chin Wee TaniD· 2 shared Hanna AbbergeriD· 2 shared Kelly L. RogersiD· 2 shared Raymond Z. QiniD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersImmunology

Bailey E. WilliamsORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CXCL9-Dependent Immune Networks of Spontaneous Tertiary Lymphoid Structures in a Murine Subcutaneous Tumor Model

Raymond Z. Qin, Hanna Abberger, Guigui Man, Benjamin J. Broomfield, Bailey E. Williams, Chin Wee Tan, Brigette C. Duckworth, Misty Rayna Jenkins, Niall D. Geoghegan, Kelly L. Rogers, Zewen Kelvin Tuong, Joanna R. Groom

This study develops a subcutaneous tumor model that naturally forms tertiary lymphoid structures (TLS) and identifies CXCL9 as a key regulator of TLS formation and function.

bioRxiv · Oct 18, 2026 · PreprintImmunology

ARAP2 regulates responses to interferon-gamma by restricting SOCS1

Narelle Keating, Karen Doggett, Grace M. Bidgood, Lizeth G. Meza Guzman, Laura F. Dagley, Kunlun Li, Bailey E. Williams, Anna Gabrielyan, Carolina Alvarado, Benjamin J. Broomfield, Brigette C. Duckworth, Colin Hockings, Jumana M. Yousef, Evelyn Leong, Rhiannon Morris, , Sandra E. Nicholson

This study identifies ARAP2 as a regulator of IFN-gamma signaling by modulating SOCS1 function through a phosphorylation-dependent interaction.

Cell Reports · Dec 1, 2025Peer-reviewedCell Biology

Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection

Benjamin J. Broomfield, Chin Wee Tan, Raymond Z. Qin, Hanna Abberger, Brigette C. Duckworth, Carolina Alvarado, Lennard Dalit, Chee Leng Lee, Rekha Shandre Mugan, Zihnil Adha Islamy Mazrad, Hiromi Muramatsu, Liana Mackiewicz, Bailey E. Williams, Jinjin Chen, Asuka Takanashi, , Joanna R. Groom

This paper shows that temporarily blocking type I interferon during viral infection boosts CD8+ T cell memory and vaccine effectiveness by promoting TSCM cell formation.

The Journal of Experimental Medicine · Feb 5, 2025Peer-reviewedImmunology