Author

Mark R. Flory

Oregon Health & Science UniversityORCID 0000-0002-6174-2708Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:experimental assay· 1 Assay:imaging· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Jessie May Cartier· 2 shared Alexander E. DaviesiD· 1 shared Amy Gross· 1 shared Beyza CengiziD· 1 shared Carol M. R. Halsey· 1 shared Elise C. ManaloiD· 1 shared GEORGE V. THOMASiD· 1 shared Hugo Cros· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Jessie May Cartier

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 2, 2026

Spatially coordinated RTK-ERK signaling dynamics shape osteosarcoma single-cell drug response in the lung microenvironment

Rawan Makkawi, Carol M. R. Halsey, Vaibhav Murthy…·Alexander E. Davies

This study identifies FGFR-ERK signaling as a driver of adaptive resistance in osteosarcoma lung metastases and shows that combinatorial RTK inhibition enhances MCL1 inhibitor efficacy.

DOI 10.64898/2026.09.30.755770

humanimaging

Cancer BiologyMetabolitesPeer-reviewedJun 12, 2025

Mitochondrial Translation Inhibition Uncovers a Critical Metabolic-Epigenetic Interface in Renal Cell Carcinoma

Kazumi H Eckenstein, Beyza Cengiz, Matthew E.K. Chang…·GEORGE V. THOMAS

This study shows that tigecycline inhibits mitochondrial translation in RCC, disrupts bioenergetics, and synergizes with entinostat to enhance anti-tumor effects.

3 citations

humanproteomics