Author

Vaibhav Murthy

Oregon Health & Science UniversityORCID 0000-0002-4171-2296Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Organism:mouse· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Alexander E. DaviesiD· 3 shared Jeremy CoppermaniD· 3 shared Carol M. R. Halsey· 2 shared Elise C. ManaloiD· 2 shared Francis Anderson· 2 shared Rawan MakkawiiD· 2 shared Ting ZhengiD· 2 shared Amy Gross· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersCancer Biology

Alexander E. DaviesORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 2, 2026

Spatially coordinated RTK-ERK signaling dynamics shape osteosarcoma single-cell drug response in the lung microenvironment

Rawan Makkawi, Carol M. R. Halsey, Vaibhav Murthy…·Alexander E. Davies

This study identifies FGFR-ERK signaling as a driver of adaptive resistance in osteosarcoma lung metastases and shows that combinatorial RTK inhibition enhances MCL1 inhibitor efficacy.

DOI 10.64898/2026.09.30.755770

humanimaging

𝕏 PostBluesky

BioengineeringbioRxivPreprintAug 4, 2026

A Compact, Standalone & Battery-Powered 3D Organoid-on-Chip System with Programmable Flow Control

Raviraj Thakur, Vaibhav Murthy, Samuel Olsen…·Alexander E. Davies

The paper introduces a compact, battery-powered organoid-on-chip system with programmable flow control, validated for culturing pancreatic cancer organoids and showing enhanced proliferation and drug response.

DOI 10.64898/2026.08.02.742326

mouseorganoid / primary culture

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Cancer BiologybioRxivPreprintSep 8, 2025

Serial Imaging of Tumour and microEnvironment (SITE) platform for live-cell ex vivo modelling of primary and metastatic cancer dynamics

Vaibhav Murthy, Rawan Makkawi, Francis Anderson…·Alexander E. Davies

The paper introduces the SITE platform for live-cell ex vivo modeling of cancer and TME interactions, revealing tissue-specific dynamics and ERK signaling patterns in breast cancer.

3 citations

humanimaging

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