Author

Rawan Makkawi

Oregon Health & Science UniversityORCID 0000-0002-8301-3688Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alexander E. DaviesiD· 2 shared Carol M. R. Halsey· 2 shared Elise C. ManaloiD· 2 shared Jeremy CoppermaniD· 2 shared Vaibhav MurthyiD· 2 shared Amy Gross· 1 shared Francis Anderson· 1 shared Gabriella TangkilisaniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Alexander E. DaviesORCID

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2 papers

Recent·Most cited

Spatially coordinated RTK-ERK signaling dynamics shape osteosarcoma single-cell drug response in the lung microenvironment

Rawan Makkawi, Carol M. R. Halsey, Vaibhav Murthy, Elise C. Manalo, Hugo Cros, Xin Yi, Jessie May Cartier, Matthew Chang, Mark R. Flory, Kelly Guptell, Amy Gross, Ryan David Roberts, Jeremy Copperman, Alexander E. Davies

This study identifies FGFR-ERK signaling as a driver of adaptive resistance in osteosarcoma lung metastases and shows that combinatorial RTK inhibition enhances MCL1 inhibitor efficacy.

bioRxiv · Oct 2, 2026 · PreprintCancer Biology

Serial Imaging of Tumour and microEnvironment (SITE) platform for live-cell ex vivo modelling of primary and metastatic cancer dynamics

Vaibhav Murthy, Rawan Makkawi, Francis Anderson, Carol M. R. Halsey, Elise C. Manalo, Sanjay Srikanth, Gabriella Tangkilisan, Ting Zheng, James C. McGann, Marc R. Birtwistle, Jeremy Copperman, Alexander E. Davies

The paper introduces the SITE platform for live-cell ex vivo modeling of cancer and TME interactions, revealing tissue-specific dynamics and ERK signaling patterns in breast cancer.

bioRxiv · Sep 8, 2025 · PreprintCancer Biology