Author

Elise C. Manalo

Oregon Health & Science UniversityORCID 0000-0003-2752-5280Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Assay:imaging· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Alexander E. DaviesiD· 2 shared Carol M. R. Halsey· 2 shared Dmytro Grygoryev· 2 shared Jeremy CoppermaniD· 2 shared Jungsun KimiD· 2 shared Mark Berry· 2 shared Rawan MakkawiiD· 2 shared Rosalie C. SearsiD· 2 shared

Activity by Year

2023-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

Alexander E. DaviesORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 2, 2026

Spatially coordinated RTK-ERK signaling dynamics shape osteosarcoma single-cell drug response in the lung microenvironment

Rawan Makkawi, Carol M. R. Halsey, Vaibhav Murthy…·Alexander E. Davies

This study identifies FGFR-ERK signaling as a driver of adaptive resistance in osteosarcoma lung metastases and shows that combinatorial RTK inhibition enhances MCL1 inhibitor efficacy.

DOI 10.64898/2026.09.30.755770

humanimaging

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Cancer BiologybioRxivPreprintSep 8, 2025

Serial Imaging of Tumour and microEnvironment (SITE) platform for live-cell ex vivo modelling of primary and metastatic cancer dynamics

Vaibhav Murthy, Rawan Makkawi, Francis Anderson…·Alexander E. Davies

The paper introduces the SITE platform for live-cell ex vivo modeling of cancer and TME interactions, revealing tissue-specific dynamics and ERK signaling patterns in breast cancer.

3 citations

humanimaging

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Cancer BiologybioRxivPreprintJun 25, 2025

Long Noncoding RNAs Preserve Pancreatic Cancer Identity and Resist Cell Fate Conversion

Dmytro Grygoryev, Seung-Won Lee, Connor Mitchell Frankston…·Jungsun Kim

This study identifies long noncoding RNAs as key regulators of pancreatic cancer identity and resistance to reprogramming.

DOI 10.1101/2025.06.25.661419

humanDNA methylation

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Cell BiologyCellular and Molecular Gastroenterology and HepatologyPeer-reviewedJan 1, 2025

HMG Box-Containing Protein 1 (HBP1) Protects Against Pancreatic Injury in Acute Pancreatitis but Promotes Neoplastic Progression.

Seung-Won Lee, Taelor J. Ekstrom, Elise C. Manalo…·Jungsun Kim

This study shows HBP1 protects against acute pancreatitis but promotes pancreatic cancer progression in the presence of KRAS mutations.

1 citation

mousehuman

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Synthetic BiologybioRxivPreprintSep 27, 2023

Engineered Lactiplantibacillus plantarum as a Biosensor Probe for the Lungs

Michael D. Brasino, Eli Wagnell, Elise C. Manalo…·Justin L. Merritt

This paper demonstrates a genetically engineered Lactiplantibacillus plantarum strain as a biosensor for detecting lung disease by secreting a detectable biomarker in urine.

DOI 10.1101/2023.09.27.559779

mouseexperimental assay

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