This study identifies distinct ferroptosis gene signatures in gastric adenocarcinoma and adjacent tissues, revealing transcriptional heterogeneity and regulatory imbalances.

bioRxiv · Sep 11, 2025 · PreprintCancer Biology

Characterization of Human Endogenous Retroviruses in Gastric Cancer with Helicobacter pylori: A Study from Northern Brazil

Marcos da Conceição, Juliana Barreto Albuquerque Pinto, Diego Pereira, Rubem Ferreira da Silva, Sérgio Augusto Antunes Ramos, Daniel de Souza Avelar, Jéssica Manoelli Costa da Silva, Ronald Matheus da Silva Mourão, Valéria Cristiane Santos da Silva, Samir Mansour Moraes Casseb, Sâmia Demachki, Tatiane Neotti, Ana Karyssa Mendes Anaissi, Williams Fernandes Barra, Amanda Ferreira Vidal, , Fabiano Cordeiro Moreira

This study characterizes HERV expression in gastric cancer tissues and finds differential expression in tumor samples, particularly those with H. pylori infection.

bioRxiv · Sep 6, 2025 · PreprintGenetics

Viral Landscape of Gastric Adenocarcinoma Reveals Clinically Relevant Viruses

Diego Pereira, Fabiano Cordeiro Moreira, Daniel de Souza Avelar, Sérgio Augusto Antunes Ramos, Valéria Cristiane Santos da Silva, Jéssica Manoelli Costa da Silva, Ronald Matheus da Silva Mourão, Rubem Ferreira da Silva, Kaue Sant Ana Pereira Guimaraes, Juliana Barreto Albuquerque Pinto, Marcos da Conceição, Williams Fernandes Barra, Sâmia Demachki, Samir Mansour Moraes Casseb, Rommel Mário Rodríguez Burbano, Paulo Pimentel de Assumpção

The paper identifies viral species in gastric tumor and peritumoral tissues, finding enriched viruses and comparable diversity between tissue types.

bioRxiv · Sep 5, 2025 · PreprintGenetics