Paulo Pimentel de Assumpção

This study identifies ANPEP as upregulated in gastric adenocarcinoma and associated with immune suppression and tumor progression, suggesting its potential as a biomarker and therapeutic target.

This study compares microbial diversity, immune cell composition, and gene expression in gastric adenocarcinoma and peritumoral tissue to identify functional differences in their microenvironments.

This study analyzes mutational profiles in gastric adenocarcinoma samples from northern Brazil using NGS, identifying key mutations and patterns associated with replication damage and DNA repair.

This study identifies molecular subtypes of gastric adenocarcinoma that correlate with prognosis but find that neither histology nor a derived signature alone reliably stratifies survival.

This study examines how the FLOT chemotherapy regimen affects the gastric tumor microenvironment, revealing subtype-specific microbiome-host interactions that influence tumor behavior.

This study identifies distinct ferroptosis gene signatures in gastric adenocarcinoma and adjacent tissues, revealing transcriptional heterogeneity and regulatory imbalances.

This study characterizes HERV expression in gastric cancer tissues and finds differential expression in tumor samples, particularly those with H. pylori infection.

The paper identifies viral species in gastric tumor and peritumoral tissues, finding enriched viruses and comparable diversity between tissue types.

The paper introduces a pipeline for functional microbiome profiling using NGS data, showing improved performance over existing methods in analyzing gastric cancer-associated microbiomes.

The paper uses coexpression network analysis on RNA-seq data to identify key hub genes and modules associated with gastric adenocarcinoma, revealing potential diagnostic biomarkers and tumor microenvironment interactions.

This study uses RNA-seq to analyze gene expression in EBV-positive and EBV-negative gastric cancer samples, identifying differentially expressed genes and viral gene activity associated with tumor progression.

The paper presents a database of SARS-CoV-2 targets for siRNA approaches, providing sequences and features to aid in antiviral development.

The paper investigates ACE2 polymorphisms in South American and global populations to explain sex and ancestry-related differences in COVID-19 outcomes.

The paper characterizes the transcriptome of Arapaima gigas using multi-tissue RNA-sequencing to identify tissue-specific and sex-biased gene expression patterns.

The paper investigates TMPRSS2 genetic variation in East Asian and European populations to assess its role in susceptibility and outcomes of COVID-19.