Developmental BiologyProceedings of the National Academy of SciencesPeer-reviewed
NOTUM-MEDIATED WNT SILENCING DRIVES EXTRAVILLOUS TROPHOBLAST CELL LINEAGE DEVELOPMENT
Vinay Shukla, Ayelen Moreno‐Irusta, Kaela M. Varberg…·Michael J. Soares
This study shows that NOTUM downregulates WNT signaling to drive EVT cell differentiation from human trophoblast stem cells, essential for placental development and healthy pregnancy.
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