Lucas Massier

The paper creates a single-cell transcriptome atlas of human subcutaneous adipose tissue vascular cells, identifies sub-AdECs, and links their properties to metabolic disease.

This study identifies diet-temperature interactions that shape DNA methylation and gene regulation in brown adipose tissue, showing obesity limits cold-induced transcriptional responses.

This study creates a spatiotemporal proteomic map of human adipogenesis, revealing changes in protein abundance, localization, and metabolic pathway reprogramming during adipocyte differentiation.