Anna‐Lena Steckelberg

Structure providers for 18 CASP16 nucleic acid targets find blind predictions capture secondary structure but miss non-canonical interactions, backbone kinks, ligand sites, and intermolecular interfaces.

The paper determines the structure of a plant-virus xrRNA and shows it forms a pseudoknot that confers exoribonuclease resistance, revealing a conserved mechanism across diverse viruses.

The paper shows Ku suppresses RNA-mediated innate immune responses in human cells, enabling primate-specific Alu element expansion by reducing dsRNA-induced inflammation.