Vahid Asnafi

This study identifies Epromoters involved in 3D promoter-promoter interactions that regulate gene expression and are critical for T-ALL cell survival.

This study identifies clonal lymphocyte expansions and JAK-STAT mutations in celiac disease subtypes, revealing shared mechanisms and limitations of JAK inhibitor therapy.

This study identifies ALDH1A2 as a therapeutic target in T-ALL, showing its essential role in leukemic cell survival and demonstrating potent anti-leukemic activity with Dimate inhibition.

The paper identifies H3K4me3 broad domains formed by super-enhancer translocations in B-cell and T-cell malignancies, linking them to oncogene activation.