Andreas Zanzoni

The paper presents a manually curated dataset of protein binding domains, linking them to molecular interactions and genomic variations for benchmarking and disease mechanism studies.

The paper reports a large-scale quantitative interactome of human PDZ domains and bacterial PDZ-binding motifs, showing bacteria tailor effector sequences to bind with similar or higher affinity than human PBMs to hijack host functions.

BactMentha is a database of annotated bacteria-host protein interactions for human, mouse, and rat, including virulence proteins and predicted interaction interfaces.

This study identifies Epromoters involved in 3D promoter-promoter interactions that regulate gene expression and are critical for T-ALL cell survival.

mimicINT identifies microbe-host protein interactions by detecting molecular mimicry elements, showing effectiveness in analyzing bacterial and viral interactions with human proteins.

This study identifies and characterizes the functional roles of microproteins (sPEPs) in three human tissues, revealing two distinct functional groups and their regulatory roles.

The paper maps binary SARS-CoV-2 protein interactions with host proteins, identifying key processes like immune signaling and ubiquitination, and suggests therapeutic targets.

The paper investigates 3’UTR-protein complexes in human multifunctional proteins, finding they regulate localization and multifunctionality by enabling diverse interactions.

The paper identifies candidate virulence proteins of Fusobacterium nucleatum that interact with human proteins involved in inflammatory bowel disease and colorectal cancer.