Cellas A. Hayes

This study investigates the role of IGF-1 signaling in neurons and astrocytes in ischemic stroke, finding that while both contribute to protection, neither is essential for minimizing tissue damage or behavioral outcomes.

This study examines how IGF-1 signaling affects glutamate-induced toxicity and oxidative stress in neuron, astrocyte, and endothelial cells of the neuro-glio-vascular unit, showing differential responses across cell types.

This study shows that reducing IGF-1R in adult hippocampal neurons impairs spatial learning and memory in male mice but not females, with structural changes in dendritic boutons and altered signaling pathways.