ImmunologyFrontiers in ImmunologyPeer-reviewed
CD28 Shapes T Cell Receptor Signaling by Regulating ZAP70 Activation and Lck Dynamics
Kumarkrishna Raychaudhuri, Rohita Rangu, Alison Ma…·Lawrence E. Samelson
This study shows CD28 co-stimulation accelerates ZAP70 recruitment and activation in TCR microclusters by enhancing Lck dynamics and spatial separation of Lck species.
16 citations