Author

Luke B. Snell

St Thomas' HospitalORCID 0000-0002-6263-9497Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Jeffrey SeowiD· 2 shared Katie J. DooresiD· 2 shared Adela Alcolea-Medina· 1 shared Alison Helen HolmesiD· 1 shared Carl Graham· 1 shared Christine Peters· 1 shared David George PartridgeiD· 1 shared Emma C. ThomsoniD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

Jeffrey SeowORCID

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3 papers

Recent·Most cited

MicrobiologyCell Reports MedicinePeer-reviewedFeb 1, 2026

Antibody escape drives emergence of diverse spike haplotypes resembling variants of concern in persistent SARS-CoV-2 infections

Luke B. Snell, Suzanne Pickering, Adela Alcolea-Medina…·Rui Pedro Galão

The paper identifies diverse spike haplotypes in persistent SARS-CoV-2 infections that show immune escape mechanisms similar to variants of concern.

1 citation

humanwhole-genome sequencing

ImmunologyPLoS PathogensPeer-reviewedNov 18, 2024

Profiling serum immunodominance following SARS-CoV-2 primary and breakthrough infection reveals distinct variant-specific epitope usage and immune imprinting.

Jeffrey Seow, George C.E. Jefferson, Michael D. Keegan…·Katie J. Doores

This study maps epitope immunodominance in sera following SARS-CoV-2 primary and breakthrough infections, revealing variant-specific epitope usage and immune imprinting effects.

6 citations

humanproteomics

Genetic & Genomic MedicinemedRxivPreprintJun 15, 2022

How acceptable is rapid whole genome sequencing for infectious disease management in hospitals? Perspectives of those involved in managing nosocomial SARS-CoV-2

Paul Flowers, Julie McLeod, Fiona Mapp…·Judith Breuer

The paper explores the acceptability of rapid whole genome sequencing for managing nosocomial SARS-CoV-2 infections through interviews with healthcare professionals.

3 citations

viruswhole-genome sequencing